jbogaerts

Jan Bogaerts earned his degree in mathematics (1986) and his PhD in mathematics (1993) at the Free University of Brussels (Belgium). In 1988 he also earned a degree in management at the Free University in Brussels. From 1986 to 1993 he worked as an assistant in mathematics and statistics at the faculties of Economic, Social and Political Sciences and of Science at Free University of Brussels. In 1993 he joined BMS as statistician, and was later promoted Associate Director Statistics. In this position he worked on the development of several drugs in oncology, including several FDA and EMEA submissions. In 2004 he joined the EORTC as statistician of the EORTC Breast Cancer Group. In 2004 he was appointed senior statistician and in 2010 Head of the Statistics department. He was a contributor to the development of version 1.1 of RECIST and is on the RECIST Steering Committee. He represents EORTC as course director of the Flims workshop. Another key role is as the statistician of the MINDACT trial EORTC 0041– BIG 3-04 (Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy: A prospective, randomized study comparing the 70- gene signature with the common clinicalpathological criteria in selecting patients for adjuvant chemotherapy in breast cancer with 0 to 3 positive nodes) which recently closed accrual. Current statistical interests include the use of and methodological issues around Progression Free Survival, alternative ways to use changes in tumor measurements as predictive markers, and the correct evaluation of the contribution of new markers to existing prognostic risk evaluation.