Clinical Trial Details
EORTC-24051-HNCG
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Phase I/II study on induction chemotherapy followed by chemoradiation with or without lapatinib, a dual EGFR/ErbB2 kinase inhibitor, in patients with locally advanced resectable larynx and hypopharynx squamous cell.
Trial Status | All trial activities ended |
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Dates |
Date of activation: 09-May-2007 Date Step1 close: 04-Nov-2008 |
Data management at EORTC | Yes |
Design |
Phase 1-2 Randomized open label |
Targeted Sample size | All Groups: 127 |
Treatment |
Radiotherapy, Drug Fluorouracil, Carboplatin, Cisplatin, Docetaxel, Lapatinib |
Study Staff | |
Type of cancer | Head and Neck |
Participating groups | EORTC Head and Neck Cancer Group |
Recruiting centers |
Institut Jules Bordet (Anderlecht, Belgium) Universitair Ziekenhuis Antwerpen (Edegem, Belgium) |
Protocol summary | http://clinicaltrials.gov/study/NCT00498953 |
NCT number | NCT00498953 |
EudraCT | 2006-002667-33 |
Financial Support | Educational Grant |