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Phase III study on larynx preservation comparing induction chemotherapy and radiotherapy versus alternating chemo-radiotherapy in resectable hypopharynx and larynx cancers (Jointly with the EORTC Radiotherapy Cooperative Group)

Study documentation Publications

Trial Status LT-FU ongoing
Dates Date of activation: 23-Jul-1996
Date Step1 close: 15-May-2004
Data management at EORTC Yes
Design Phase 3
Randomized open
Targeted Sample size EORTC Groups: 564
Treatment Radiotherapy, Surgery, Drug
Study Staff Jean-Claude Horiot (Study Coordinator) , Clinique De Genolier, Genolier
Jean-Louis Lefebvre (Study Coordinator) , Centre Oscar Lambret, Lille
Carmela Caballero (Clinical Research Physician) carmela.caballero (at), EORTC Headquarters, Brussels
Julie Coupain (Regulatory Affairs Manager) julie.coupain (at), EORTC Headquarters, Brussels
Nathalie Crokart (Pharmacovigilance Manager) nathalie.crokart (at), EORTC Headquarters, Brussels
Livia Giurgea (Data Manager) livia.giurgea (at), EORTC Headquarters, Brussels
Dominiek Staelens (Project Manager) dominiek.staelens (at), EORTC Headquarters, Brussels
Type of cancer Head and Neck
Participating groups EORTC Head and Neck Cancer Group
EORTC Radiation Oncology Group
Participating centers
Protocol summary
NCT number NCT00002839