Clinical Trial Details

EORTC-40004

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CLOCC trial (Chemotherapy + Local ablation versus Chemotherapy). Randomized phase II study investigating the role of local treatment of liver metastases by radiofrequency combined with chemotherapy and of chemotherapy alone in patients with unresectable colorectal liver metastases.

Study documentation Publications

Trial Status All trial activities ended
Dates Date of activation: 16-Apr-2002
Date Step1 close: 20-Jun-2007
Data management at EORTC Yes
Design Phase 2
Randomized open label
Targeted Sample size All Groups: 152
Treatment Fluorouracil, Bevacizumab, Leucovorin, Oxalilplatin
Study Staff
Type of cancer
Participating groups EORTC Gastrointestinal Tract Cancer Group
Arbeitsgruppe Lebermeta.und -tum.Chir.Arbeitsgem.Onko-DE
National Cancer Research Inst. -Colorectal Cancer Group-UK
Protocol summary http://clinicaltrials.gov/ct/show/NCT00043004
NCT number NCT00043004