Recruiting

Date of activation: 11-Nov-2022

Yes

Phase 2
Randomized open label

EORTC Groups: 205 - All Groups: 205

Drug
Cisplatin, Vincristine, Lomustine, Sonidegib

• Peter Hau (Study Coordinator), Universitaetsklinikum Regensburg, Regensburg
• Jessica Berger (Clinical Research Associate/Monitor), EORTC Headquarters, Brussels
• Jose Casas (TR Scientist), EORTC Headquarters, Brussels
• Enrico Clementel (QART Manager), EORTC Headquarters, Brussels
• Corneel Coens (Statistician), EORTC Headquarters, Brussels
• Luminita Copaceanu (Lead CRA), EORTC Headquarters, Brussels
• Coreen Corning (QART Manager), EORTC Headquarters, Brussels
• Hazal Erkol (Data Manager), EORTC Headquarters, Brussels
• Beatrice Fournier (Clinical Scientist), EORTC Headquarters, Brussels
• Irina Ghislain (QoL Specialist), EORTC Headquarters, Brussels
• Thierry Gorlia (Statistician), EORTC Headquarters, Brussels
• Lore Hermans (Regulatory Affairs Manager), EORTC Headquarters, Brussels
• Sarah Kelly (QART Manager), EORTC Headquarters, Brussels
• Hafida Lmalem (Imaging Officer), EORTC Headquarters, Brussels
• Livia Meirsman (Project Manager), EORTC Headquarters, Brussels
• Sara Meloen (Pharmacovigilance Manager), EORTC Headquarters, Brussels
• Caroline Quoilin (Clinical Scientist), EORTC Headquarters, Brussels
• Jose Silva (Medical representative, Clinical Research Physician), EORTC Headquarters, Brussels
• Luiza Souza (QART Manager), EORTC Headquarters, Brussels
• Maarten Spruyt (Data Manager), EORTC Headquarters, Brussels
• Laurien Vancleef (Clinical Operations Manager), EORTC Headquarters, Brussels
• Xiao Mang Zhou (Regulatory Affairs Manager), EORTC Headquarters, Brussels

• Brain

• EORTC Brain Tumor Group
• Cooperative Trials Group for Neuro-Oncology
• Neuroonkologische Arbeitsgemeinschaft

• A.O Landeskrankenhaus - Innsbruck Universitaetsklinik (Innsbruck, Austria)
• Austin Health - Austin hospital (Heidelberg VIC, Australia)
• CHU de Nice - Hopital Pasteur (NICE, France)
• CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole (TOULOUSE CEDEX 9, France)
• Centre Leon Berard (Lyon, France)
• Charite - Universitaetsmedizin Berlin - Campus Mitte (Berlin, Germany)
• Charite - Universitaetsmedizin Berlin - Campus Virchow-Klinikum (Berlin, Germany)
• Erasmus MC (Rotterdam, Netherlands)
• HELIOS Klinikum Erfurt GmbH (Erfurt, Germany)
• Hopital de La Timone (APHM) (MARSEILLE, France)
• Hospital Clinic de Barcelona (Barcelona, Spain)
• ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia) (Badalona - (Barcelona), Spain)
• Klinikum Rechts der isar Der Technische Universitaet Muenchen - Klinikum Rechts Der Isar (Muenchen, Germany)
• Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern (Muenchen, Germany)
• Peter Maccallum Cancer Institute (Melbourne, Australia)
• Prince Of Wales Hospital (Randwick - Sydney, Australia)
• Princess Alexandra Hospital - University Of Queensland (Woolloongabba, Brisbane, Australia)
• Royal Adelaide Hospital (Adelaide, Australia)
• Royal North Shore Hospital (St Leonards, Australia)
• Staedtisches Klinikum Muenchen - Klinikum Schwabing (Muenchen, Germany)
• Sydney Children's Hospital (Randwick, Australia)
• Univ. Knappschaft Krankenhaus Bochum (Bochum-Langendreer, Germany)
• UniversitaetsKlinikum Heidelberg - Head Hospital (Heidelberg, Germany)
• UniversitaetsMedizin Mannheim (Mannheim, Germany)
• Universitaetsklinikum - Essen (Essen, Germany)
• Universitaetsklinikum Bonn (Bonn, Germany)
• Universitaetsklinikum Carl Gustav Carus (TUD) (Dresden, Germany)
• Universitaetsklinikum Freiburg - Klinik fuer Neurochirurgie (Freiburg, Germany)
• Universitaetsklinikum Freiburg - Zentrum fuer Kinder u Jugend med. (Freiburg, Germany)
• Universitaetsklinikum Hamburg-Eppendorf KE - University Cancer Center (Hamburg, Germany)
• Universitaetsklinikum Leipzig-Klinik fuer Strahlentherapie und Radioonkologie (Leipzig, Germany)
• Universitaetsklinikum Regensburg (Regensburg, Germany)
• Universitaetsklinikum Tuebingen- Crona Kliniken (Tuebingen, Germany)
• Universitaetsklinikum Wien - AKH unikliniken (Vienna, Austria)
• Universitaetsmedizin Goettingen - Georg-August Universitaet (Goettingen, Germany)
• Universitaetsmedizin der Johannes Gutenberg Universitaet Mainz-University Medical Center (Mainz, Germany)
• University Hospital Frankfurt -Senckenberg Institute of Neurooncology (Frankfurt am Main, Germany)
• Westmead Hospital - Crown Princess Mary Cancer Center (Westmead, Australia)

• APHP Sorbonne Univ - Hopital la Pitie-Salpetriere (PARIS, France)
• AUSL Bologna - Ospedale Bellaria (Bologna, Italy)
• Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale San Giovanni - Dipartimento Neuroscienze (Torino, Italy)
• CHRU de Lille (LILLE CEDEX, France)
• Centre Hospitalier Universitaire Vaudois - Lausanne (Lausanne, Switzerland)
• Gustave Roussy (VILLEJUIF CEDEX, France)
• Hospital Universitari Vall d’Hebron -Vall d'Hebron Institut Oncologia (Barcelona, Spain)
• Hospital Universitario 12 De Octubre (Madrid, Spain)
• Hospital Universitario Ramon y Cajal (Madrid, Spain)
• IRCCS - Istituto Neurologico Carlo Besta (Milano, Italy)
• Institut de Cancerologie de l’Ouest (ICO) - Saint Herblain (Saint Herblain CEDEX, France)
• John Hunter Children’s Hospital (Newcastle, Australia)
• Odense University Hospital (Odense C, Denmark)
• Sir Charles Gairdner Hospital (Nedlands, Australia)
• ULSS2 - Marca Trevigniana (Treviso, Italy)
• Univ. of Florence -Azienda Ospedaliero-Universitaria Careggi (Firenze, Italy)
• UniversitaetsSpital Zurich - Neurology Clinic (Zurich, Switzerland)
• Universitaetsklinikum- Heidelberg HOPP Kindertumorzentrum (Heidelberg, Germany)
• University Medical Center Groningen (Groningen, Netherlands)

http://clinicaltrials.gov/study/NCT04402073

NCT04402073

2020-003063-26