Whether prospectively or retrospectively, EORTC also carries research programs addressing specific challenges of modern oncology as well as developing knowledge from the wealth of its databases. Molecular screening programs for access precision medicine studies are now fully integrated in the EORTC infrastructure. Similarly, addressing medical and societal challenges that patients face after the disease has become crucial as our success to control the disease are improving. Clinical research today is a multifaceted discipline where varying programs do support and feed into each other in a comprehensive manner to foster more rapidly knowledge development into therapeutic benefit. EORTC has made the successful transition to integrate such complementarity into its scientific agenda.