Recruiting

Date of activation: 23-May-2025

Yes

Phase 3
Randomized open label

Drug
Goserelin, Abiraterone, Triptorelin, Leuprorelin, Enzalutamide, Degarelix, Apalutamide, Darolutamide, Relugolix, Akeega

• Bertrand Tombal (Study Coordinator), Cliniques Universitaires Saint-Luc, Brussels
• Silke Gillessen (Study Co-Coordinator), Oncology Institute of Southern Switzerland - Ospedale San Giovanni, Bellinzona
• Guillaume Grisay (Y-ECI Coordinator), CHU Helora Pole Hospitalier Jolimont - Hopital Jolimont, Haine-Saint-Paul
• Fabio Turco (Y-ECI Coordinator), Oncology Institute of Southern Switzerland - Ospedale San Giovanni, Bellinzona
• Egle Venslovaite (Project Manager), EORTC Headquarters, Brussels
• Bert Dhondt (Clinical Research Physician), EORTC Headquarters, Brussels
• Beatrice Fournier (Clinical Scientist), EORTC Headquarters, Brussels
• Olga Basova (Statistician), EORTC Headquarters, Brussels
• Jammbe Musoro (Statistician), EORTC Headquarters, Brussels
• Jerome Rapion (Statistical Analyst), EORTC Headquarters, Brussels
• Cedric Mallien (TR Scientist), EORTC Headquarters, Brussels
• Joanna Krzystyniak (Clinical Operations Manager), EORTC Headquarters, Brussels
• Sophie Roulet (Junior Clinical Operations Manager), EORTC Headquarters, Brussels
• Kacper Sierocki (Junior Clinical Operations Manager), EORTC Headquarters, Brussels
• Lore Meelberghs (Data Manager), EORTC Headquarters, Brussels
• Bart Meulemans (Data Manager), EORTC Headquarters, Brussels
• Tim Verbiest (Data Manager), EORTC Headquarters, Brussels
• Peter De Burghgraeve (Study Designer), EORTC Headquarters, Brussels
• Sara Meloen (Pharmacovigilance Manager), EORTC Headquarters, Brussels
• Sandrine Rivrain (Pharmacovigilance Manager), EORTC Headquarters, Brussels
• Gilles Sarlet (Regulatory Affairs Manager), EORTC Headquarters, Brussels
• Katheline Vander Heggen (Junior RAM), EORTC Headquarters, Brussels
• Christine Bourguignon (Clinical Operations Assistant), EORTC Headquarters, Brussels
• Stephane Lejeune (International Affairs and Policies Manager), EORTC Headquarters, Brussels
• Ahu Alanya (QoL Specialist), EORTC Headquarters, Brussels

• Prostate

• EORTC Genito-Urinary Cancers Group
• Swiss Cancer Institute (formerly Schweizerisches Arbeitsgemeinschaft Klin. Krebsforschung)
• Groupe d'Etude des Tumeurs Uro-Genitales
• Spanish Oncology Genito-Urinary Group
• Cancer Trials Ireland

• APHP Centre - Univ de Paris Cite - Hopital Europeen Georges Pompidou (PARIS, France)
• APHP Nord - Univ De Paris Cite - Hop. Saint Louis (Paris, France)
• Beacon Hospital (Dublin 18, Ireland)
• Beaumont Hospital (Dublin, Ireland)
• Brust-Zentrum AG Zurich (Zurich, Switzerland)
• CH de La Cote Basque - Saint Leon (Bayonne, France)
• CHR d'Orleans - Hopital De La Source (ORLEANS CEDEX 2, France)
• CHU Helora Pole Hospitalier Jolimont - Hopital Jolimont (Haine-Saint-Paul, Belgium)
• CHU Mont Godinne - UCL Namur (Yvoir, Belgium)
• CHU de Lyon - Hopital Edouard Herriot (LYON, France)
• CHU de Lyon - Hopital Lyon Sud (PIERRE BENITE CEDEX, France)
• CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole (TOULOUSE, France)
• CHU de Tours - Hopital Bretonneau (Tours, France)
• Cantonal Hospital Olten (Olten, Switzerland)
• Centre Eugene Marquis (RENNES CEDEX, France)
• Centre Francois Baclesse (CLCC) (CAEN CEDEX 5, France)
• Centre Leon Berard (Lyon, France)
• Clinique La Croix Du Sud (Quint-Fonsegrives, France)
• Clinique Pasteur-Lanroze (BREST, France)
• Cliniques Universitaires Saint-Luc (Brussels, Belgium)
• Cork University Hospital (Cork, Ireland)
• Grand Hopital de Charleroi - Site Les Viviers (Gilly, Belgium)
• Groupe Hosp. St Vincent -Clinique Ste Anne (Strasbourg, France)
• Groupe Hospitalier Mutualiste de Grenoble-Institut Daniel Hollard (Grenoble, France)
• Groupe Hospitalier Paris Saint-Joseph - Hopital Saint Joseph (Paris, France)
• Gustave Roussy (VILLEJUIF CEDEX, France)
• HOCH Health Ostschweiz-Kantonsspital St Gallen (St Gallen, Switzerland)
• Hirslanden Klinik-Tumor Zentrum Aarau (Aarau, Switzerland)
• Hopitaux Universitaires de Strasbourg - Hôpital civil (STRASBOURG CEDEX, France)
• Hopitaux universitaires de Geneve - HUG - site de Cluse-Roseraie (Geneve, Switzerland)
• Hospital Clinic de Barcelona (Barcelona, Spain)
• Hospital De La Santa Creu I Sant Pau (Barcelona, Spain)
• Hospital Del Mar (Barcelona, Spain)
• Hospital Universitari Son Espases (Palma De Mallorca, Spain)
• Hospital Universitario 12 De Octubre (Madrid, Spain)
• Hospital Universitario Central De Asturias (Oviedo, Spain)
• Hospital Universitario De Cruces (Barakaldo (Bizkaia), Spain)
• Hospital Universitario Marques De Valdecilla (Santander, Spain)
• Hospital Universitario Puerta De Hierro (Majadahonda, Spain)
• Hospital Universitario Ramon y Cajal (Madrid, Spain)
• Hospital Universitario Regional de Malaga (Malaga, Spain)
• Hospital Universitario Reina Sofia (Cordoba, Spain)
• Hospital Universitario San Carlos (Madrid, Spain)
• Hospital Universitario Virgen De La Victoria (Malaga, Spain)
• Hospital Universitario de La Princesa (Madrid, Spain)
• Hospital Universitario de Navarra (Pamplona, Spain)
• Institut Curie- Hopital de Paris (PARIS CEDEX 05, France)
• Institut Godinot (REIMS CEDEX, France)
• Institut Mutualiste Montsouris (Paris, France)
• Institut Paoli-Calmettes (MARSEILLE CEDEX 09, France)
• Institut du Cancer de Montpellier (MONTPELLIER CEDEX 5, France)
• Kantonsspital Frauenfeld- Breast Unit Thurgau (Frauenfeld, Switzerland)
• Kantonsspital Graubuenden (Chur, Switzerland)
• Klinicki bolnicki Centar Sestre Milosrdnice - (Grad Zagreb, Croatia)
• Les Hopitaux Civils de Colmar (COLMAR CEDEX, France)
• Luzerner Kantonsspital (Luzern, Switzerland)
• Mater Misericordia University Hospital (Dublin, Ireland)
• Oncology Institute of Southern Switzerland - Ospedale San Giovanni (Bellinzona, Switzerland)
• Parc Tauli Hospital Universitari (Sabadell Barcelona, Spain)
• Rigshospitalet (Copenhagen, Denmark)
• Spital STS AG Thun (Thun, Switzerland)
• St. Claraspital (Basel, Switzerland)
• St. James'S Hospital (Dublin, Ireland)
• Stadtspital Zurich Triemli (Zurich, Switzerland)
• Tallaght University Hospital (Dublin, Ireland)
• U.Z. Leuven - Campus Gasthuisberg (Leuven, Belgium)
• UniversitaetsSpital Zurich (Zurich, Switzerland)
• Universitair Ziekenhuis Gent (Gent, Belgium)
• University Hospital Galway (Galway, Ireland)
• University Hospital Limerick (Limerick, Ireland)
• University Hospital Virgen del Rocio (Sevilla, Spain)

• APHP - Hop. Univ. Henri Mondor (Creteil, France)
• AZ Delta - Campus Rumbeke (Roeselare, Belgium)
• Azienda Unita Locale Socio-Sanitaria N. 9-Mater Salutis Hospital (Legnago, Italy)
• CHU de Brest (Brest, France)
• CLCC - Jean Perrin (CLERMONT FERRAND , France)
• Centre Georges-Francois-Leclerc (DIJON CEDEX, France)
• Centre Hospitalier Universitaire Vaudois - Lausanne (Lausanne, Switzerland)
• Centre Oscar Lambret (LILLE CEDEX, France)
• Clinique Hartmann (Neuilly-Sur-Seine, France)
• Fakultni nemocnine Brno - Univ. Hospital Brno (Brno, Czech Republic)
• Heilig Hartziekenhuis Lier (Lier, Belgium)
• Herlev Hospital - University Copenhagen (Herlev, Denmark)
• Hospital Clinico Universitario De Valladolid (Valladolid, Spain)
• Hospital General Universitario Gregorio Maranon (Madrid, Spain)
• Hospital Riviera-Chablais (Rennaz, Switzerland)
• Hospital San Pedro de Alcantara (Caceres, Spain)
• Hospital Universitario Lucus Augusti (Lugo, Spain)
• Hospital da Luz - Lisboa (Lisboa, Portugal)
• Hospital prive du Confluent - Centre Catherine de Sienne (NANTES CEDEX 2, France)
• ICO L’Hospitalet - Hospital Duran i Reynals (Institut Catala D'Oncologia) (L' Hospitalet De Llobregat, Spain)
• IRCCS-Regina Elena National Cancer Center (Roma, Italy)
• Institut Bergonie (Bordeaux, France)
• Institut Jules Bordet (Anderlecht, Belgium)
• Institut de Cancerologie de Lorraine (VANDOEUVRE LES NANCY CEDEX, France)
• Institut de Cancerologie de l’Ouest (ICO) - Angers (ANGERS CEDEX 02, France)
• Institut de Cancerologie de l’Ouest (ICO) - Saint Herblain (Saint Herblain CEDEX, France)
• Istituto Europeo di Oncologia (Milano, Italy)
• Kantonsspital Baden (Baden, Switzerland)
• Kantonsspital Winterthur (Winterthur, Switzerland)
• Mater Private Hospital (Dublin 7, Ireland)
• Medisprof Cancer Center srl (Cluj-Napoca, Romania)
• Oncomed S.R.L Hospital (Timisoara, Romania)
• Ospedale Fatebenefratelli Isola Tiberina Gemelli Isola (Roma, Italy)
• Ospedale P. Pederzoli Casa Di Cura Privata (Peschiera Del Garda, Italy)
• Santa Maria della Misericordia Hospital (Perugia, Italy)
• St. Vincent'S University Hospital (Dublin 4, Ireland)
• The Institute Of Oncology (Ljubljana, Slovenia)
• Univ. of Florence -Azienda Ospedaliero-Universitaria Careggi (Firenze, Italy)
• University Hospital Of Olomouc (Olomouc, Czech Republic)

http://clinicaltrials.gov/study/NCT05974774

NCT05974774