Study
EORTC-1913-LYMG
A randomised phase III trial with a PET response adapted design comparing ABVD +/- ISRT with A2VD +/- ISRT in patients with previously untreated stage IA/IIA Hodgkin lymphoma.
Trial Status
Recruiting
Dates
Date of activation: 01-Mar-2024
Data management at EORTC
No
Design
Phase 3
Randomized open label
Randomized open label
Treatment
Drug
Bleomycin, Dacarbazine, Doxorubicin, Vinblastine, Brentuximab vedotin
Bleomycin, Dacarbazine, Doxorubicin, Vinblastine, Brentuximab vedotin
Study Staff
- Martin Hutchings (Study Coordinator), Rigshospitalet, Copenhagen
- Sanne Tonino (Study Co-Coordinator), Amsterdam UMC stichting - Locatie AMC, Amsterdam
- Hanne Locy (Project Manager), EORTC Headquarters, Brussels
- Ward Sents (Clinical Scientist), EORTC Headquarters, Brussels
- Catherine Fortpied (Statistician), EORTC Headquarters, Brussels
- Boubker Ait Brik (Clinical Operations Manager), EORTC Headquarters, Brussels
- Anna Fleming (Pharmacovigilance Manager), EORTC Headquarters, Brussels
- Sandrine Rivrain (Pharmacovigilance Manager), EORTC Headquarters, Brussels
- Leslie Herman (Regulatory Affairs Manager), EORTC Headquarters, Brussels
- Nathalie Ropson (Regulatory Affairs Manager), EORTC Headquarters, Brussels
- Amelie Baudhuin (Adm Ass COM), EORTC Headquarters, Brussels
Type of cancer
- Hodgkins Disease
Participating groups
- EORTC Lymphoma Group
- University College of London
Recruiting centers
- AZ Delta - Campus Rumbeke (Roeselare, Belgium)
- Amsterdam UMC stichting - locatie VUMC (Amsterdam, Netherlands)
- CHU Site Sainte-Elisabeth-UCL Namur (Namur, Belgium)
- Haaglanden MC - locatie Antoniushove ( Leidschendam, Netherlands)
- Hospital Del Mar (Barcelona, Spain)
- Hospital Universitario de Navarra (Pamplona, Spain)
- ICO L’Hospitalet - Hospital Duran i Reynals (Institut Catala D'Oncologia) (L' Hospitalet De Llobregat, Spain)
- Instituto Portugues de Oncologia de Lisboa Francisco Gentil – EPE (Lisboa, Portugal)
- Narodny Onkologicky Ustav - Bratislava (Bratislava, Slovakia)
- Radboud University Medical Center Nijmegen (Nijmegen, Netherlands)
- Region Midtjylland - Aarhus University Hospital-Skejby (Aarhus, Denmark)
- Reinier De Graaf Gasthuis (Delft, Netherlands)
- Rigshospitalet (Copenhagen, Denmark)
- St. James'S Hospital (Dublin, Ireland)
- St. Vincent'S University Hospital (Dublin 4, Ireland)
- U.Z. Leuven - Campus Gasthuisberg (Leuven, Belgium)
- Universitair Ziekenhuis Antwerpen (Edegem, Belgium)
- University Hospital Galway (Galway, Ireland)
- University Medical Center Groningen (Groningen, Netherlands)
- ZAS CADIX (Antwerpen, Belgium)
Protocol summary
NCT number
NCT04685616
