Study

EORTC-62092-22092-STBSG-ROG

A phase III randomized study of preoperative radiotherapy plus surgery versus surgery alone for patients with Retroperitoneal sarcomas (RPS) - STRASS

Study documentation Back to result

Trial Status

LT-FU ongoing

Dates

Date of activation: 16-Jan-2012
Date Step1 close: 11-Apr-2017

Data management at EORTC

Yes

Design

Phase 3
Randomized open label

Targeted Sample size

EORTC Groups: 256 - All Groups: 256

Treatment

Radiotherapy, Surgery

Study Staff

  • Sylvie Bonvalot (Study Coordinator), Institut Curie- Hopital de Paris, PARIS CEDEX 05
  • Rick Haas (Study Coordinator), The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis, Amsterdam
  • Enrico Clementel (QART Manager), EORTC Headquarters, Brussels
  • Laura De Meulemeester (Senior Clinical Operations Manager), EORTC Headquarters, Brussels
  • Stephanie Kromar (Regulatory Affairs Manager), EORTC Headquarters, Brussels
  • Saskia Litiere (Statistician), EORTC Headquarters, Brussels
  • Sandrine Marreaud (Clinical Research Physician), EORTC Headquarters, Brussels
  • Zara Nasir (Pharmacovigilance Manager), EORTC Headquarters, Brussels
  • Axelle Nzokirantevye (Data Manager), EORTC Headquarters, Brussels
  • Sandrine Rivrain (Pharmacovigilance Manager), EORTC Headquarters, Brussels

Type of cancer

  • Soft Tissue and Bone Sarcoma

Participating groups

  • EORTC Radiation Oncology Group
  • EORTC Soft Tissue and Bone Sarcoma Group

Recruiting centers

  • CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole (TOULOUSE CEDEX 9, France)
  • Centre Hospitalier de l'Université de Montreal - Hopital Notre-Dame (Montreal, Canada)
  • Centre Leon Berard (Lyon, France)
  • Centro Di Riferimento Oncologico (Aviano, Italy)
  • Dana-Farber Cancer Institute & Harvard Medical School (Boston, United States of America)
  • Gustave Roussy (VILLEJUIF CEDEX, France)
  • Herlev Hospital - University Copenhagen (Herlev, Denmark)
  • Hospital Universitari Vall d’Hebron -Vall d'Hebron Institut Oncologia (Barcelona, Spain)
  • Hospital Universitario San Carlos (Madrid, Spain)
  • IRCCS - Fondazione Istituto Nazionale dei Tumori (Milano, Italy)
  • IRCCS - Istituto Oncologico Veneto (Padova, Italy)
  • Institut Bergonie (Bordeaux, France)
  • Institut Curie- Hopital de Paris (PARIS CEDEX 05, France)
  • Institut Jules Bordet (Anderlecht, Belgium)
  • Istituto Clinico Humanitas (Rozzano, Milano, Italy)
  • Karolinska University Hospital, location Solna (Stockholm Solna, Sweden)
  • Klinikum Rechts der isar Der Technische Universitaet Muenchen - Klinikum Rechts Der Isar (Muenchen, Germany)
  • Leeds Teaching Hospitals NHS Trust - St. James's University Hospital (Leeds, United Kingdom)
  • Leiden University Medical Centre (Leiden, Netherlands)
  • Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern (Muenchen, Germany)
  • Mount Sinai Hospital (Toronto, Ontario, Canada)
  • NHS Lothian - Western General Hospital (Edinburgh, United Kingdom)
  • Newcastle Hospitals NHS Trust - Freeman Hospital, Northern Centre For Cancer Care (Newcastle upon Tyne, United Kingdom)
  • Nottingham University Hospitals NHS Trust - City Hospital (Nottingham, United Kingdom)
  • Oslo University Hospital - Radiumhospitalet (Oslo, Norway)
  • Radboud University Medical Center Nijmegen (Nijmegen, Netherlands)
  • Royal Marsden Hospital - Chelsea, London (London, United Kingdom)
  • Sheffield Teaching Hospitals NHS Foundation Trust - Weston Park Hospital (Sheffield, United Kingdom)
  • The Christie NHS Foundation Trust (Manchester, United Kingdom)
  • The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis (Amsterdam, Netherlands)
  • U.Z. Leuven - Campus Gasthuisberg (Leuven, Belgium)
  • UHB-Queen Elizabeth Medical Centre (Birmingham, United Kingdom)
  • UniversitaetsMedizin Mannheim (Mannheim, Germany)
  • Universitaetsklinikum Koeln (Koeln, Germany)
  • University College Hospital (London, United Kingdom)
  • University Hospitals Bristol NHS Foundation Trust - Bristol Haematology And Oncology Centre (Bristol, United Kingdom)
  • University Medical Center Groningen (Groningen, Netherlands)

Centers to be activated

  • CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole (TOULOUSE CEDEX 9, France)

Protocol summary

http://clinicaltrials.gov/study/NCT01344018

NCT number

NCT01344018