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A phase III randomized study of preoperative radiotherapy plus surgery versus surgery alone for patients with Retroperitoneal sarcomas (RPS) - STRASS

Study documentation

Trial Status LT-FU ongoing
Dates Date of activation: 16-Jan-2012
Date Step1 close: 11-Apr-2017
Data management at EORTC Yes
Design Phase 3
Randomized open label
Targeted Sample size EORTC Groups: 256 - All Groups: 256
Treatment Radiotherapy, Surgery
Study Staff Sylvie Bonvalot (Study Coordinator) , Institut Curie- Hopital de Paris, PARIS CEDEX 05
Rick Haas (Study Coordinator) , The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis, Amsterdam
Stephanie Kromar (Regulatory Affairs Manager) , EORTC Headquarters, Brussels
Saskia Litiere (Statistician) , EORTC Headquarters, Brussels
Sandrine Marreaud (Clinical Research Physician) , EORTC Headquarters, Brussels
Axelle Nzokirantevye (Data Manager) , EORTC Headquarters, Brussels
Sandrine Rivrain (Pharmacovigilance Manager) , EORTC Headquarters, Brussels
Ionela Stanciu (Clinical Operations Manager) , EORTC Headquarters, Brussels
Type of cancer Soft Tissue and Bone Sarcoma
Participating groups EORTC Radiation Oncology Group
EORTC Soft Tissue and Bone Sarcoma Group
Recruiting centers CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole (TOULOUSE CEDEX 9, France)
Centre Hospitalier de l'Université de Montreal - Hopital Notre-Dame (Montreal, Canada)
Centre Leon Berard (Lyon, France)
Centro Di Riferimento Oncologico (Aviano, Italy)
Dana-Farber Cancer Institute & Harvard Medical School (Boston, United States of America)
Gustave Roussy (VILLEJUIF CEDEX, France)
Herlev Hospital - University Copenhagen (Herlev, Denmark)
Hospital Universitari Vall d’Hebron -Vall d'Hebron Institut Oncologia (Barcelona, Spain)
Hospital Universitario San Carlos (Madrid, Spain)
IRCCS - Fondazione Istituto Nazionale dei Tumori (Milano, Italy)
IRCCS - Istituto Oncologico Veneto (Padova, Italy)
Institut Bergonie (Bordeaux, France)
Institut Curie- Hopital de Paris (PARIS CEDEX 05, France)
Institut Jules Bordet (Brussels, Belgium)
Istituto Clinico Humanitas (Rozzano, Milano, Italy)
Karolinska University Hospital, location Solna (Stockholm, Sweden)
Leeds Teaching Hospitals NHS Trust - St. James's University Hospital (Leeds, United Kingdom)
Leiden University Medical Centre (Leiden, Netherlands)
Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern (Muenchen, Germany)
Mount Sinai Hospital (Toronto, Ontario, Canada)
NHS Lothian - Western General Hospital (Edinburgh, United Kingdom)
Newcastle Hospitals NHS Trust - Freeman Hospital, Northern Centre For Cancer Care (Newcastle upon Tyne, United Kingdom)
Nottingham University Hospitals NHS Trust - City Hospital (Nottingham, United Kingdom)
Oslo University Hospital - Radiumhospitalet (Oslo, Norway)
Radboud University Medical Center Nijmegen (Nijmegen, Netherlands)
Royal Marsden Hospital - Chelsea, London (London, United Kingdom)
Sheffield Teaching Hospitals NHS Foundation Trust - Weston Park Hospital (Sheffield, United Kingdom)
Technische Universitaet Muenchen - Klinikum Rechts Der Isar (Muenchen, Germany)
The Christie NHS Foundation Trust (Manchester, United Kingdom)
The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis (Amsterdam, Netherlands)
U.Z. Leuven - Campus Gasthuisberg (Leuven, Belgium)
UHB-Queen Elisabeth Medical Centre (Birmingham, United Kingdom)
UniversitaetsMedizin Mannheim (Mannheim, Germany)
Universitaetsklinikum Koeln (Koeln, Germany)
University College Hospital (London, United Kingdom)
University Hospitals Bristol NHS Foundation Trust - Bristol Haematology And Oncology Centre (Bristol, United Kingdom)
University Medical Center Groningen (Groningen, Netherlands)
Centers to be activated CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole (TOULOUSE CEDEX 9, France)
Protocol summary
NCT number NCT01344018
Financial Support Academic Fund
External Grant