Description
Endocrine tumours encompasses thyroid carcinomas and adrenal cancers.
The Endocrine Tumours Group focuses on thyroid cancer bringing together endocrinologists and oncologists to conduct clinical studies.
Main Achievements
- Launched a survey on the genotyping of thyroid cancer in Europe. A total of 86 practitioners from 18 European Union countries, Switzerland and Turkey responded. Most of them regularly require somatic molecular genotyping. Lack of reimbursement (46.7%), lack of established workflow (46.7%) and lack of access to targeted therapies (40%) were the main reasons not to perform somatic mutations screening.
- Launched a second survey with the Head and Neck Cancer Group on the management of anaplastic thyroid cancer (ATC) in Europe. A total of 94 institutions from 20 countries responded. The results showed that 30 centres evaluate ≥ 5 ATC pts/y with a global incidence >200 pts/y. 80.8% test BRAF. Most clinicians complained about the limitations in drug prescription and only 13.8% have clinical trials ongoing. The results clearly show that ATC still represents a huge unmet need.
- Presented both surveys at the ESMO meeting 2021. Hosted our Group biannual meetings virtually due to Covid-19. Thyroid cancer patients participated for the first time to share about their quality of life and clinical experiences.
This group has been trying to get clinical trials activated, and there is now one trial open to patient recruitment and another large trans-Atlantic collaboration in development with ITOG in the USA.
Research Group
Group documents-
Chair
Laura Locati
Istituti Clinici Scientifici Maugeri
Pavia, Italy
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Secretary
Christelle De La Fouchardière
Institut Paoli-Calmettes
Marseille, France
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Treasurer
Marek Dedecjus
Maria Sklodowska-Curie National Research Institute of Oncology
Warsaw, Poland
Steering committee
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L. Locati - Pavia, IT
Istituti Clinici Scientifici Maugeri
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M. Dedecjus - Warsaw, PL
Maria Sklodowska-Curie National Research Institute of Oncology
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P. Soares - Porto, PT
IPATIMUP
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C. De La Fouchardière - Marseille, FR
Institut Paoli-Calmettes
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R. Netea-Maier - Nijmegen, NL
Radboud University Medical Center
Notable Publications
All publications on this research field-
2023
Current picture of Anaplastic Thyroid Cancer patients' care and meetable needs: a survey of 94 Institutions from the EORTC Endocrine and Head and Neck Cancer Groups
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2022
Position paper from the Endocrine Task Force of the European Organization for Research and Treatment of Cancer (EORTC) on the management and shared decision making in patients with low-risk micro papillary thyroid carcinoma