The ETF is initiating a biobank for peripheral blood to study potential ageing biomarkers. Given the paucity of large clinical trials currently running in the elderly population, it is of crucial importance to create a European biobank of biological samples which can be used for future research projects. Initially this will involve the collection and storage of blood samples. Ageing markers of interest are: telomere length, expression of p16 in peripheral leukocytes, circulating Il-6, TNF-α and IL-10, single nucleotide polymorphisms (SNPs) in several age related genes such as apoE and FOXO3A genes, age related miRNA expression, and age related gene expression profiling.
A template protocol for biobanking in elderly trials has been established that can be built into different protocols.