Pathobiology

EORTC has implemented a cross group policy for biobanking

EORTC research has resulted in the clinical qualification of uPA/PAI-1 as a class 1 level-of-evidence biomarkers for the prognosis of node-negative breast cancer patients. These biomarkers were subsequently recommended by national and international guidelines.

It has also contributed to the validation of gene-expression profiles and to the discovery of mechanisms of breast cancer metastasis leading to more personalised treatment for this cancer.

In addition, our pathobiology research has guided the development of robust, reliable and cost-effective assays applicable for routine clinical testing.